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10L/30L/50L Pilot Scale SIP Fermentation System

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Code: 10L/30L/50L Pilot Scale SIP Fermentation System
Brand: Major Science
Category: > Cell System
Description:

 The 10L / 30L / 50L SIP Pilot Scale Fermentation Systems allows you to run small volume of fermentation experiments with ease. These systems are perfectly suitable for small scaling-up in the academic lab. The easy programming and operation on our Winpact software makes your operation procedure in your peace of mind. This fermenter comes with rolling wheels for mobility. All materials are made from the highest standard to ensure optimization of your fermentation process. A variety of optional devices are also available to maintain your optimum performance.




Utility Requirement

In situ drain; ≥ 1"

Capacity

10 L

30 L

50 L

Power

Three phase 220V or 380V (note: can be customized to local standard)

Air

At least 6 bar

30 L/min flow rate

90 L/min flow rate

150 L/min flow rate

Dehumidified

Oil-free

Peripheral factory water supply

Cooling water (tap water, at least 15oC below working temperature, must be soft water) ;
Pressure at least 2 bar

Process water

RO Water

Plant steam

≥ 2 bar; dry steam with no entrained condensate

Process steam

≥ 2 bar; dry steam with no entrained condensate

Drain


Capacity

10 L

30 L

50 L

Total volume

15 L

42 L

67 L

Working volume

10 L

30 L

50 L

Vessel and jacket maximum working pressure

3 bar (43.5 psig) / 4 bar (58 psig)

Type

Double layered fully enclosed capsule-type tank

Material

Direct contact to medium - 316L stainless steel; all others - 304 stainless steel

Surface finish

Interior polish  25 Ra/in (0.6 μm) Mechanical polishing; Electropolish optional
Exterior polish 
 32 Ra/in (0.8 μm) Mechanical polishing; Electropolish optional

Ports

Ports designed according to user requirements

Piping and valve materials

Parts that directly contact with the product/medium uses 316L stainless steel (≤25 Ra/in) internal polished tubing (BPE standard) :
A.) Internal EP polished diaphragm type pneumatic valve and manual valve (BPE standard)
B.) Tubing all welded with orbital welding
C.) Vessel bottom drain uses a diaphragm valve, to minimize dead volume
D.) Piping designed for ease of transfer to scale up (can be used as a seed fermentation system) or downstream process

Parts that do not directly contact product/medium
A.)
Constructed with 304 stainless steel

Controller

10.4” color industrial touch screen

* User-friendly, graphical control interface
* Includes secure user accounts, with different levels of access
* Modularized and standardized design (Module Skid): ergonomically designed according to height, ease of vessel clean
   up,  and ease of extraction in relation to vessel bottom valve
* Includes maintenance page with system diagnostics
* All programmed setting values are automatically stored into the built-in memory; the settings will not be lost in case of power outage/interruption. When power is restored, the interrupted process will automatically resume

Setting

* Automated sterilization process
* Automated fermentation program

DO

* 0-200%, Control range:0-100%, adjustable
* Software electrode calibration, with automatic temperature compensation function
* Includes one set of side-inserted stainless steel autoclavable DO electrode
* DO Stat features with intelligent feeding

pH

* PID control with adjustable deadband
* Control range0 to 14 (2-12 for maximum precision), resolution: 0.01 pH
* Calibration function with automatic temperature compensation function
* Includes one set of side-inserted, autoclavable pH probe with stainless steel housing
* pH Stat features with intelligent feeding

Pump

* Built-in peristaltic pumps

* Each feeding pump can run adjustable 15-step program
* Each pump can be adjusted for speed, forward and backward direction, and manual or automatic mode
* Each of the four peristaltic pumps can be designated for different functions: acid pump, base pump, antifoam pump, or 
   substrate feeding pump
* Optional fifth and six peristaltic pump available

Temperature

* Vessel temperature is measured with a side-inserted PT-100 temperature probe and maintained using PID control.
* Control range: 0-130°C, ±0.1°C. Operational range up to 0-60°C

Agitation

* Manual or automatic control of agitation speed
* 15-step program to change speed, or use DO cascade control

Air supply and exhaust

Gas supply and dehumidifer: uses in-house air compressor or air dehumidifier
* Includes re-useable, autoclavable 0.2μm air filter for gas inlet
* Gas Inlet (air)
    Includes mass flow controller:
    2 vvm maximum according to the vessel capacity
* Gas Inlet (oxygen)
   Includes pure oxygen rotameter (manual flow control):
   1 vvm maximum according to the vessel capacity
* Includes oxygen gas solenoid valve, with automatic pulsed time control

Air outlet / Exhaust
* Exhaust port with stainless steel condenser
* Includes re-useable, autoclavable 0.2μm air filter
* Includes automated adjustable gas outlet valve to adjust vessel back pressure
* Can control manually or automatically via software

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